“A new “Trojan Horse” nanoparticle can eat away portions of the plaques that cause heart attacks, research in mice indicates.
The discovery could be a potential treatment for atherosclerosis, a leading cause of death in the United States.
The nanoparticle homes in on atherosclerotic plaque due to its high selectivity to a particular immune cell type—monocytes and macrophages.
Once inside the macrophages in those plaques, it delivers a drug agent that stimulates the cell to engulf and eat cellular debris. Basically, it removes the diseased/dead cells in the plaque core. By reinvigorating the macrophages, it reduces and stabilizes plaque size…”