A New CRISPR Technique Let Researchers Repair a Genetic Mutation in Viable Human Embryos

A New CRISPR Technique Let Researchers Repair a Genetic Mutation in Viable Human Embryos

“A new CRISPR technique could prevent humans from passing on a potentially life-threatening disorder, according to Chinese researchers.

The Chinese researchers didn’t use CRISPR in the typical way, though. Instead, they tried something called “base editing,” a technique that scientists have known about since 2016. With base editing, the CRISPR system simply changes one DNA letter to another (for example, swapping an A for a G). Previous studies have shown that base editing appears to cause fewer unwanted edits than the traditional method. But they weren’t sure it would work on human DNA.

The researchers behind the current study decided to test base editing on the mutation that causes Marfan Syndrome, because all it should take to correct it is changing the G in the FBN1 gene to a healthy A.

And it mostly seemed go as planned…”

https://futurism.com/base-editing-crispr-marfan/

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